Wednesday, May 16, 2018

Judges Playing Scientists

Superior Court Judge Elihu Berle, argued that roasters and manufacturers failed to prove that that there is no substantial risk to drinking coffee, or that the benefits of drinking the beverage outweigh the risks posed by acrylamide, a substance created naturally during the brewing process. By the standards of California’s decades-old Proposition 65 law, Berle affirmed in his final ruling last week, all coffee sold in California must come with a warning label stating: WARNING: This product contains chemicals known to the State of California to cause cancer and birth defects or other reproductive harm. *

An example of scientific ignorance and misguided judgement.

If coffee should be labeled as carcinogenic, then so should toast, grilled meat, pizza crust, and a plethora of other foods that contain a lot of carbohydrates and proteins.

BUT it is ‘okay’ to ingest foods that have been exposed to pesticides demonstrated to be neurotoxins and carcinogens, and drink water tainted with the same, without the same warnings!

The Maillard reaction that occurs during heating or breakdown of certain substrates does produce acrylamide (and free radicals). It is basic organic chemistry. Is it carcinogenic? It can be, depending on dose and the animal. This is based on experiments with mice, but not with humans. Although mice are not men (murine models have limitations for extrapolation to humans), using mice can lead to suggestive conclusions that then must be tested in humans. Pharmacology history is fraught with failures in extrapolation from mice to humans.

Should we be concerned? Possibly, if you are drinking a gallon or more of coffee every day. The greatest threat from anything involving the Maillard reaction products, including acrylamide, is smoking! And uncontrolled blood glucose levels.

The Maillard reaction that occurs from smoke inhalation and rampant metabolism of glucose and proteins in tissues causes exceedingly high free radical production and Amadori products which accelerate breakdown of connective tissue in the body (elastin and collagen in skin, tendons, ligaments, vascular tissue, eyes, etc.). That’s why smokers have accelerated aging of their skin, and it is a contribution to diabetic pathophysiology.

We shouldn’t expect judges to be scientists, but we should expect them to consult with experts in the field in which rulings are concerned.

Interesting that they don’t exert the same concern and rulings with documented toxins in our environment, other than those spurious claims.

* In Labeling Coffee a Carcinogen, California Leaps Ahead of the Science

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